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α - synuclein and Parkinson’s disease: the first roadblock
α-synuclein gene mutations are major underlying genetic defects known in familial juvenile onset Parkinson’s disease (PD), and α-synuclein is a major constituent of Lewy Bodies, the pathological hallmark of PD. The normal cellular function of α-synuclein has been elusive, and its exact etiological m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley & Sons, Ltd
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933078/ http://dx.doi.org/10.2755/jcmm010.004.04 |