N-Acetyl-L-Cysteine abrogates fibrogenic properties of fibroblasts isolated from Dupuytren's disease by blunting TGF-β signalling

Dupuytren's disease, a benign fibroproliferative disorder of the palmar fascia, represents an ideal model to study tissue fibrosis. Transforming growth factor-β(1) (TGF-β(1)) and its downstream Smad signalling system is well established as a key player during fibrogenesis. Thus, targeting this...

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Detalles Bibliográficos
Autores principales: Kopp, Jürgen, Seyhan, Harun, Müller, Bastian, Lanczak, Johanna, Pausch, Elke, Gressner, Axel M, Dooley, Steven, Horch, Raymund E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2006
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933108/
https://www.ncbi.nlm.nih.gov/pubmed/16563228
http://dx.doi.org/10.1111/j.1582-4934.2006.tb00297.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933108/
https://www.ncbi.nlm.nih.gov/pubmed/16563228
http://dx.doi.org/10.1111/j.1582-4934.2006.tb00297.x

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