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Protein carbonylation, cellular dysfunction, and disease progression
Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a widespread indicator of severe oxidative damage and disease-derived protein dysfunction. Whereas moderately carbonylated proteins are degraded by the proteasomal system,...
Autores principales: | Dalle-Donne, Isabella, Aldini, Giancarlo, Carini, Marina, Colombo, Roberto, Rossi, Ranieri, Milzani, Aldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933129/ https://www.ncbi.nlm.nih.gov/pubmed/16796807 http://dx.doi.org/10.1111/j.1582-4934.2006.tb00407.x |
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