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Role of ROBO4 Signalling in Developmental and Pathological Angiogenesis

Transmembrane roundabout receptor family members (ROBO1–ROBO4) principally orchestrate the neuronal guidance mechanism of the nervous system. Secreted glycoprotein SLITs are the most appreciated ligands for ROBOs. Recently identified ROBO4 is the key mediator of SLIT-ROBO mediated developmental and...

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Detalles Bibliográficos
Autores principales: Yadav, Suresh Singh, Narayan, Gopeshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933320/
https://www.ncbi.nlm.nih.gov/pubmed/24689049
http://dx.doi.org/10.1155/2014/683025