Cellular responses of BRCA1-defective and triple-negative breast cancer cells and in vitro BRCA1 interactions induced by metallo-intercalator ruthenium(II) complexes containing chloro-substituted phenylazopyridine

BACKGROUND: Triple-negative breast cancer (TNBC) is defined by the absence of expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2. Breast cancers with a BRCA1 mutation are also frequently triple-negative. Currently, there is a lack of effective therapi...

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Detalles Bibliográficos
Autores principales: Nhukeaw, Tidarat, Temboot, Pornvichai, Hansongnern, Kanidtha, Ratanaphan, Adisorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933379/
https://www.ncbi.nlm.nih.gov/pubmed/24507701
http://dx.doi.org/10.1186/1471-2407-14-73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933379/
https://www.ncbi.nlm.nih.gov/pubmed/24507701
http://dx.doi.org/10.1186/1471-2407-14-73

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