DNA repair in cancer: emerging targets for personalized therapy

Genomic deoxyribonucleic acid (DNA) is under constant threat from endogenous and exogenous DNA damaging agents. Mammalian cells have evolved highly conserved DNA repair machinery to process DNA damage and maintain genomic integrity. Impaired DNA repair is a major driver for carcinogenesis and could...

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Detalles Bibliográficos
Autores principales: Abbotts, Rachel, Thompson, Nicola, Madhusudan, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933425/
https://www.ncbi.nlm.nih.gov/pubmed/24600246
http://dx.doi.org/10.2147/CMAR.S50497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933425/
https://www.ncbi.nlm.nih.gov/pubmed/24600246
http://dx.doi.org/10.2147/CMAR.S50497

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