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T Cell Receptor Signaling Can Directly Enhance the Avidity of CD28 Ligand Binding

T cell activation takes place in the context of a spatial and kinetic reorganization of cell surface proteins and signaling molecules at the contact site with an antigen presenting cell, termed the immunological synapse. Coordination of the activation, recruitment, and signaling from T cell receptor...

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Detalles Bibliográficos
Autores principales: Sanchez-Lockhart, Mariano, Rojas, Ana V., Fettis, Margaret M., Bauserman, Richard, Higa, Trissha R., Miao, Hongyu, Waugh, Richard E., Miller, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933428/
https://www.ncbi.nlm.nih.gov/pubmed/24586641
http://dx.doi.org/10.1371/journal.pone.0089263