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RAGE Controls Activation and Anti-Inflammatory Signalling of Protein C

AIMS: The receptor for advanced glycation endproducts, RAGE, is a multiligand receptor and NF-κB activator leading to perpetuation of inflammation. We investigated whether and how RAGE is involved in mediation of anti-inflammatory properties of protein C. METHODS AND RESULTS: We analyzed the effect...

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Detalles Bibliográficos
Autores principales: Braach, Natascha, Frommhold, David, Buschmann, Kirsten, Pflaum, Johanna, Koch, Lutz, Hudalla, Hannes, Staudacher, Kathrin, Wang, Hongjie, Isermann, Berend, Nawroth, Peter, Poeschl, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933550/
https://www.ncbi.nlm.nih.gov/pubmed/24586767
http://dx.doi.org/10.1371/journal.pone.0089422