Physiologically Based Pharmacokinetic Models in the Prediction of Oral Drug Exposure Over the Entire Pediatric Age Range—Sotalol as a Model Drug

In recent years, the increased interest in pediatric research has enforced the role of physiologically based pharmacokinetic (PBPK) models in pediatric drug development. However, an existing lack of published examples contributes to some uncertainties about the reliability of their predictions of or...

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Detalles Bibliográficos
Autores principales: Khalil, Feras, Läer, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933580/
https://www.ncbi.nlm.nih.gov/pubmed/24399240
http://dx.doi.org/10.1208/s12248-013-9555-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933580/
https://www.ncbi.nlm.nih.gov/pubmed/24399240
http://dx.doi.org/10.1208/s12248-013-9555-6

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