Multiple Renal Cyst Development but Not Situs Abnormalities in Transgenic RNAi Mice against Inv::GFP Rescue Gene

In this study we generated RNA interference (RNAi)-mediated gene knockdown transgenic mice (transgenic RNAi mice) against the functional Inv gene. Inv mutant mice show consistently reversed internal organs (situs inversus), multiple renal cysts and neonatal lethality. The Inv::GFP-rescue mice, which...

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Detalles Bibliográficos
Autores principales: Kamijho, Yuki, Shiozaki, Yayoi, Sakurai, Eiki, Hanaoka, Kazunori, Watanabe, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933642/
https://www.ncbi.nlm.nih.gov/pubmed/24586938
http://dx.doi.org/10.1371/journal.pone.0089652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933642/
https://www.ncbi.nlm.nih.gov/pubmed/24586938
http://dx.doi.org/10.1371/journal.pone.0089652

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