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Origin and Loss of Nested LRRTM/α-Catenin Genes during Vertebrate Evolution

Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) form in mammals a family of four postsynaptic adhesion proteins, which have been shown to bind neurexins and heparan sulphate proteoglycan (HSPG) glypican on the presynaptic side. Mutations in the genes encoding LRRTMs and neurexins are im...

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Detalles Bibliográficos
Autores principales: Uvarov, Pavel, Kajander, Tommi, Airaksinen, Matti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933685/
https://www.ncbi.nlm.nih.gov/pubmed/24587117
http://dx.doi.org/10.1371/journal.pone.0089910