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Synergism from the combination of ulinastatin and curcumin offers greater inhibition against colorectal cancer liver metastases via modulating matrix metalloproteinase-9 and E-cadherin expression

Liver metastasis is a major cause of mortality in colorectal cancer (CRC). The current study was to investigate the ability of ulinastatin (UTI) and curcumin (CUR) to inhibit CRC liver metastases via modulating matrix metalloproteinase-9 (MMP-9) and E-cadherin expression. Human CRC HCT-116 cells wer...

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Detalles Bibliográficos
Autores principales: Shen, Fei, Cai, Wen-Song, Li, Jiang-Lin, Feng, Zhe, Liu, Qi-cai, Xiao, Huan-qing, Cao, Jie, Xu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933719/
https://www.ncbi.nlm.nih.gov/pubmed/24570592
http://dx.doi.org/10.2147/OTT.S57126