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New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder
Vortioxetine is a novel antidepressant with effects on multiple 5-HT receptors and on the serotonin transporter. This paper reviews preclinical and clinical evidence regarding its mechanism of action, its tolerability, and its efficacy in treating major depression. Clinical studies indicate that vor...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933721/ https://www.ncbi.nlm.nih.gov/pubmed/24570588 http://dx.doi.org/10.2147/NDT.S39544 |