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Synthesis, Anti-Inflammatory and Anti- Nociceptive Activities and Cytotoxic Effect of Novel Thiazolidin-4-ones Derivatives as Selective Cyclooxygenase (COX-2) Inhibitors

Objective(s): Nowadays, COX-2 inhibitors such as valdecoxib are removed from the market because of their cardiovascular toxicity and their potential to increase the risk of strokes. In response to this, medicinal chemists have attempted to synthesize new classes of COX-2 Inhibitors. Materials and Me...

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Detalles Bibliográficos
Autores principales: Moallem, Seyed Adel, Imenshahidi, Mohsen, Shahini, Narges, Javan, Ahmad Reza, Karimi, Mohsen, Alibolandi, Mona, Ghandadi, Morteza, Etemad, Leila, Motamedshariaty, Vahidehsadat, Hosseini, Toktam, Hadizadeh, Farzin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933800/
https://www.ncbi.nlm.nih.gov/pubmed/24570829