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Two novel pathway analysis methods based on a hierarchical model

Motivation: Over the past few years several pathway analysis methods have been proposed for exploring and enhancing the analysis of genome-wide association data. Hierarchical models have been advocated as a way to integrate SNP and pathway effects in the same model, but their computational complexit...

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Detalles Bibliográficos
Autores principales: Evangelou, Marina, Dudbridge, Frank, Wernisch, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933872/
https://www.ncbi.nlm.nih.gov/pubmed/24123673
http://dx.doi.org/10.1093/bioinformatics/btt583