Cargando…
Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation
The transient receptor potential vanilloid receptor subtype I (TRPV1) channel acts as a polymodal sensory receptor gated by chemical and physical stimuli. Like other TRP channels, TRPV1 contains in its C terminus a short, conserved domain called the TRP box, which is necessary for channel gating. Su...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933934/ https://www.ncbi.nlm.nih.gov/pubmed/24567510 http://dx.doi.org/10.1085/jgp.201311070 |