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Complex role of STIM1 in the activation of store-independent Orai1/3 channels

Orai proteins contribute to Ca(2+) entry into cells through both store-dependent, Ca(2+) release–activated Ca(2+) (CRAC) channels (Orai1) and store-independent, arachidonic acid (AA)-regulated Ca(2+) (ARC) and leukotriene C(4) (LTC(4))-regulated Ca(2+) (LRC) channels (Orai1/3 heteromultimers). Altho...

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Detalles Bibliográficos
Autores principales: Zhang, Xuexin, Zhang, Wei, González-Cobos, José C., Jardin, Isaac, Romanin, Christoph, Matrougui, Khalid, Trebak, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933941/
https://www.ncbi.nlm.nih.gov/pubmed/24567509
http://dx.doi.org/10.1085/jgp.201311084