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Orexin-1 and orexin-2 receptor antagonists reduce ethanol self-administration in high-drinking rodent models
To examine the role of orexin-1 and orexin-2 receptor activity on ethanol self-administration, compounds that differentially target orexin (OX) receptor subtypes were assessed in various self-administration paradigms using high-drinking rodent models. Effects of the OX(1) antagonist SB334867, the OX...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933945/ https://www.ncbi.nlm.nih.gov/pubmed/24616657 http://dx.doi.org/10.3389/fnins.2014.00033 |