Cargando…

Research on drug resistance mechanism of trastuzumab caused by activation of the PI3K/Akt signaling pathway

AIM OF THE STUDY: To discuss the activation of the signal transduction pathway of phosphatidylinositol 3’-kinase/serine-threonine kinase (PI3K/Akt), one of the important targets of drug resistance of trastuzumab, which provides a theoretical basis for the targeted therapy of drug resistance of trast...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xi, Wang, Han, Ou-yang, Xue-nong, Xie, Fang-wei, Wu, Jing-jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934046/
https://www.ncbi.nlm.nih.gov/pubmed/24592124
http://dx.doi.org/10.5114/wo.2013.35292