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Research on drug resistance mechanism of trastuzumab caused by activation of the PI3K/Akt signaling pathway
AIM OF THE STUDY: To discuss the activation of the signal transduction pathway of phosphatidylinositol 3’-kinase/serine-threonine kinase (PI3K/Akt), one of the important targets of drug resistance of trastuzumab, which provides a theoretical basis for the targeted therapy of drug resistance of trast...
Autores principales: | Chen, Xi, Wang, Han, Ou-yang, Xue-nong, Xie, Fang-wei, Wu, Jing-jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934046/ https://www.ncbi.nlm.nih.gov/pubmed/24592124 http://dx.doi.org/10.5114/wo.2013.35292 |
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