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Diagnostic impact of promoter methylation and E-cadherin gene and protein expression levels in laryngeal carcinoma

AIM OF THE STUDY: Inactivation of the tumor suppressor E-cadherin (CDH1) and its decreased expression is an important occurrence during carcinogenesis. Nevertheless, the relationship of CDH1 expression and the promoter methylation with laryngeal cancer cell aggressiveness is still unclear. The purpo...

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Detalles Bibliográficos
Autores principales: Starska, Katarzyna, Forma, Ewa, Lewy-Trenda, Iwona, Papież, Paweł, Woś, Jan, Bryś, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934075/
https://www.ncbi.nlm.nih.gov/pubmed/24596512
http://dx.doi.org/10.5114/wo.2013.35284