RNAi-mediated Knockdown of Xist Does Not Rescue the Impaired Development of Female Cloned Mouse Embryos

In mice, one of the major epigenetic errors associated with somatic cell nuclear transfer (SCNT) is ectopic expression of Xist during the preimplantation period in both sexes. We found that this aberrant Xist expression could be impeded by deletion of Xist from the putative active X chromosome in do...

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Detalles Bibliográficos
Autores principales: OIKAWA, Mami, MATOBA, Shogo, INOUE, Kimiko, KAMIMURA, Satoshi, HIROSE, Michiko, OGONUKI, Narumi, SHIURA, Hirosuke, SUGIMOTO, Michihiko, ABE, Kuniya, ISHINO, Fumitoshi, OGURA, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934135/
https://www.ncbi.nlm.nih.gov/pubmed/23363561
http://dx.doi.org/10.1262/jrd.2012-195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934135/
https://www.ncbi.nlm.nih.gov/pubmed/23363561
http://dx.doi.org/10.1262/jrd.2012-195

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