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RNAi-mediated Knockdown of Xist Does Not Rescue the Impaired Development of Female Cloned Mouse Embryos
In mice, one of the major epigenetic errors associated with somatic cell nuclear transfer (SCNT) is ectopic expression of Xist during the preimplantation period in both sexes. We found that this aberrant Xist expression could be impeded by deletion of Xist from the putative active X chromosome in do...
Autores principales: | OIKAWA, Mami, MATOBA, Shogo, INOUE, Kimiko, KAMIMURA, Satoshi, HIROSE, Michiko, OGONUKI, Narumi, SHIURA, Hirosuke, SUGIMOTO, Michihiko, ABE, Kuniya, ISHINO, Fumitoshi, OGURA, Atsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934135/ https://www.ncbi.nlm.nih.gov/pubmed/23363561 http://dx.doi.org/10.1262/jrd.2012-195 |
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