Single-Cycle Viral Gene Expression, Rather Than Progressive Replication and Oncolysis, Is Required for VSV Therapy of B16 Melanoma

A fully intact immune system would be expected to hinder the efficacy of oncolytic virotherapy by inhibiting viral replication. Simultaneously, however, it may also enhance antitumor therapy through initiation of pro-inflammatory, antiviral cytokine responses at the tumor site. The aim of the curren...

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Detalles Bibliográficos
Autores principales: Galivo, Feorillo, Diaz, Rosa Maria, Wongthida, Phonphimon, Thompson, Jill, Kottke, Timothy, Barber, Glen, Melcher, Alan, Vile, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934361/
https://www.ncbi.nlm.nih.gov/pubmed/20016540
http://dx.doi.org/10.1038/gt.2009.161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934361/
https://www.ncbi.nlm.nih.gov/pubmed/20016540
http://dx.doi.org/10.1038/gt.2009.161

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