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Paclitaxel: new uses for an old drug

Paclitaxel (Taxol), one of the most important anticancer drugs, has been used for therapy of different types of cancers. Mechanistically, paclitaxel arrests cell cycle and induces cell death by stabilizing microtubules and interfering with microtubule disassembly in cell division. Recently, it has b...

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Detalles Bibliográficos
Autores principales: Zhang, Dongshan, Yang, Ruhao, Wang, Shixuan, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934593/
https://www.ncbi.nlm.nih.gov/pubmed/24591817
http://dx.doi.org/10.2147/DDDT.S56801