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Association between the COMTVal158Met Genotype and Alzheimer's Disease in the Han Chinese Population

BACKGROUND: Alzheimer's disease (AD) is the leading cause of dementia worldwide and is associated with individual, familial and social burdens. Catechol-O-methyltransferase (COMT) may have a prominent role in AD pathophysiology by affecting the metabolism of catecholamine neurotransmitters and...

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Detalles Bibliográficos
Autores principales: Ji, Yong, Shi, Zhihong, Liu, Mengyuan, Liu, Shuai, Liu, Shuling, Wang, Jinhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934601/
https://www.ncbi.nlm.nih.gov/pubmed/24575113
http://dx.doi.org/10.1159/000357161