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Two Case Reports of Resensitization to Previous Chemotherapy with the Novel Hypoxia-Activated Hypomethylating Anticancer Agent RRx-001 in Metastatic Colorectal Cancer Patients

The development of chemoresistance is a persistent problem during the treatment of cancer. Although reversion or modification of acquired chemoresistance has been previously observed, no systematic exploration has been undertaken. Here, we report a case study of 2 male patients, 62 and 66 years old,...

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Detalles Bibliográficos
Autores principales: Reid, T., Dad, S., Korn, R., Oronsky, B., Knox, S., Scicinski, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934615/
https://www.ncbi.nlm.nih.gov/pubmed/24575021
http://dx.doi.org/10.1159/000358382