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Mapping the Kinetic Barriers of a Large RNA Molecule's Folding Landscape
The folding of linear polymers into discrete three-dimensional structures is often required for biological function. The formation of long-lived intermediates is a hallmark of the folding of large RNA molecules due to the ruggedness of their energy landscapes. The precise thermodynamic nature of the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934814/ https://www.ncbi.nlm.nih.gov/pubmed/24586236 http://dx.doi.org/10.1371/journal.pone.0085041 |