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Honokiol Enhances Paclitaxel Efficacy in Multi-Drug Resistant Human Cancer Model through the Induction of Apoptosis

Resistance to chemotherapy remains a major obstacle in cancer therapy. This study aimed to evaluate the molecular mechanism and efficacy of honokiol in inducing apoptosis and enhancing paclitaxel chemotherapy in pre-clinical multi-drug resistant (MDR) cancer models, including lineage-derived human M...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Beitler, Jonathan J., Wang, Hong, Lee, Michael J., Huang, Wen, Koenig, Lydia, Nannapaneni, Sreenivas, Amin, A. R. M. Ruhul, Bonner, Michael, Shin, Hyung Ju C., Chen, Zhuo Georgia, Arbiser, Jack L., Shin, Dong M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934844/
https://www.ncbi.nlm.nih.gov/pubmed/24586249
http://dx.doi.org/10.1371/journal.pone.0086369