Pseudomonas-Derived Ceramidase Induces Production of Inflammatory Mediators from Human Keratinocytes via Sphingosine-1-Phosphate

Ceramide is important for water retention and permeability barrier functions in the stratum corneum, and plays a key role in the pathogenesis of atopic dermatitis (AD). A Pseudomonas aeruginosa-derived neutral ceramidase (PaCDase) isolated from a patient with AD was shown to effectively degrade cera...

Descripción completa

Detalles Bibliográficos
Autores principales: Oizumi, Ami, Nakayama, Hitoshi, Okino, Nozomu, Iwahara, Chihiro, Kina, Katsunari, Matsumoto, Ryo, Ogawa, Hideoki, Takamori, Kenji, Ito, Makoto, Suga, Yasushi, Iwabuchi, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934885/
https://www.ncbi.nlm.nih.gov/pubmed/24586752
http://dx.doi.org/10.1371/journal.pone.0089402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934885/
https://www.ncbi.nlm.nih.gov/pubmed/24586752
http://dx.doi.org/10.1371/journal.pone.0089402

Ejemplares similares