Nuclear Interaction between ADR-Induced p65 and p53 Mediates Cardiac Injury in iNOS (−/−) Mice

Adriamycin (ADR) treatment causes an imbalance in the levels of nitric oxide ((•)NO) and superoxide (O(2) (•−)) production leading to cardiac injury. Previously we demonstrated that mice lacking inducible nitric oxide synthase (iNOS) have increased oxidative stress and mitochondrial injury. The mole...

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Detalles Bibliográficos
Autores principales: Cole, Marsha P., Tangpong, Jitbanjong, Oberley, Terry D., Chaiswing, Luksana, Kiningham, Kinsley K., St. Clair, Daret K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934890/
https://www.ncbi.nlm.nih.gov/pubmed/24586632
http://dx.doi.org/10.1371/journal.pone.0089251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934890/
https://www.ncbi.nlm.nih.gov/pubmed/24586632
http://dx.doi.org/10.1371/journal.pone.0089251

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