Assessing Interactions of Two Loci (rs4242382 and rs10486567) in Familial Prostate Cancer: Statistical Evaluation of Epistasis

Understanding the impact of multiple genetic variants and their interactions on the disease penetrance of familial multiple prostate cancer is very relevant to the overall understanding of carcinogenesis. We assessed the joint effect of two loci on rs4242382 at 8q24 and rs10486567 at 7p15.2 to this...

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Detalles Bibliográficos
Autores principales: Chen, Li-Sheng, Fann, Jean Ching-Yuan, Chiu, Sherry Yueh-Hsia, Yen, Amy Ming-Fang, Wahlfors, Tiina, Tammela, Teuvo L., Chen, Hsiu-Hsi, Auvinen, Anssi, Schleutker, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934901/
https://www.ncbi.nlm.nih.gov/pubmed/24586834
http://dx.doi.org/10.1371/journal.pone.0089508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934901/
https://www.ncbi.nlm.nih.gov/pubmed/24586834
http://dx.doi.org/10.1371/journal.pone.0089508

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