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The Effect of Rosuvastatin on Inflammation, Matrix Turnover and Left Ventricular Remodeling in Dilated Cardiomyopathy: A Randomized, Controlled Trial

BACKGROUND: Dilated cardiomyopathy is characterized by left ventricular dilatation and dysfunction. Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis. Statins reduce levels of low density lipoprotein cholesterol, but may also attenuate inflammation a...

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Detalles Bibliográficos
Autores principales: Broch, Kaspar, Askevold, Erik T., Gjertsen, Erik, Ueland, Thor, Yndestad, Arne, Godang, Kristin, Stueflotten, Wenche, Andreassen, Johanna, Svendsmark, Rolf, Smith, Hans-Jørgen, Aakhus, Svend, Aukrust, Pål, Gullestad, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934914/
https://www.ncbi.nlm.nih.gov/pubmed/24586994
http://dx.doi.org/10.1371/journal.pone.0089732