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Cardiac Function and Architecture Are Maintained in a Model of Cardiorestricted Overexpression of the Prorenin-Renin Receptor

The (pro)renin-renin receptor, (P)RR has been claimed to be a novel element of the renin-angiotensin system (RAS). The function of (P)RR has been widely studied in renal and vascular pathology but the cardio-specific function of (P)RR has not been studied in detail. We therefore generated a transgen...

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Detalles Bibliográficos
Autores principales: Mahmud, Hasan, Candido, Wellington Mardoqueu, van Genne, Linda, Vreeswijk-Baudoin, Inge, Yu, Hongjuan, van de Sluis, Bart, van Deursen, Jan, van Gilst, Wiek H., Silljé, Herman H. W., de Boer, Rudolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934958/
https://www.ncbi.nlm.nih.gov/pubmed/24587131
http://dx.doi.org/10.1371/journal.pone.0089929