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Cardiac Function and Architecture Are Maintained in a Model of Cardiorestricted Overexpression of the Prorenin-Renin Receptor
The (pro)renin-renin receptor, (P)RR has been claimed to be a novel element of the renin-angiotensin system (RAS). The function of (P)RR has been widely studied in renal and vascular pathology but the cardio-specific function of (P)RR has not been studied in detail. We therefore generated a transgen...
Autores principales: | Mahmud, Hasan, Candido, Wellington Mardoqueu, van Genne, Linda, Vreeswijk-Baudoin, Inge, Yu, Hongjuan, van de Sluis, Bart, van Deursen, Jan, van Gilst, Wiek H., Silljé, Herman H. W., de Boer, Rudolf A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934958/ https://www.ncbi.nlm.nih.gov/pubmed/24587131 http://dx.doi.org/10.1371/journal.pone.0089929 |
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