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Crosslinking-Induced Endocytosis of Acetylcholine Receptors by Quantum Dots

In a majority of patients with myasthenia gravis (MG), anti-acetylcholine receptor (AChR) antibodies target postsynaptic AChR clusters and thus compromise the membrane integrity of neuromuscular junctions (NMJs) and lead to muscle weakness. Antibody-induced endocytosis of AChRs in the postsynaptic m...

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Detalles Bibliográficos
Autores principales: Lee, Chi Wai, Zhang, Hailong, Geng, Lin, Peng, H. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934987/
https://www.ncbi.nlm.nih.gov/pubmed/24587270
http://dx.doi.org/10.1371/journal.pone.0090187