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Insulin Production Hampered by Intermittent Hypoxia via Impaired Zinc Homeostasis

Without zinc, pancreatic beta cells cannot either assemble insulin molecules or precipitate insulin crystals; thus, a lack of zinc concentration in the beta cells would result in a decreased insulin production. ZIP8 is one of the zinc uptake transporters involved in zinc influx into the cytosol of b...

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Detalles Bibliográficos
Autores principales: Pae, Eung-Kwon, Kim, Gyuyoup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934988/
https://www.ncbi.nlm.nih.gov/pubmed/24587273
http://dx.doi.org/10.1371/journal.pone.0090192