Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia

Hypoxia, a state of low oxygen, is a common feature of solid tumors and is associated with disease progression as well as resistance to radiotherapy and certain chemotherapeutic drugs. Hypoxic regions in tumors, therefore, represent attractive targets for cancer therapy. To date, five distinct class...

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Detalles Bibliográficos
Autores principales: Guise, Christopher P., Mowday, Alexandra M., Ashoorzadeh, Amir, Yuan, Ran, Lin, Wan-Hua, Wu, Dong-Hai, Smaill, Jeff B., Patterson, Adam V., Ding, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935009/
https://www.ncbi.nlm.nih.gov/pubmed/23845143
http://dx.doi.org/10.5732/cjc.012.10285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935009/
https://www.ncbi.nlm.nih.gov/pubmed/23845143
http://dx.doi.org/10.5732/cjc.012.10285

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