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Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia
Hypoxia, a state of low oxygen, is a common feature of solid tumors and is associated with disease progression as well as resistance to radiotherapy and certain chemotherapeutic drugs. Hypoxic regions in tumors, therefore, represent attractive targets for cancer therapy. To date, five distinct class...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sun Yat-sen University Cancer Center
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935009/ https://www.ncbi.nlm.nih.gov/pubmed/23845143 http://dx.doi.org/10.5732/cjc.012.10285 |