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Brain-expressed 3′UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs

Why protein-coding genes express transcripts with longer 3′untranslated regions (3′UTRs) in the brain rather than in other tissues remains poorly understood. Given the established role of 3′UTRs in post-transcriptional regulation of transcript abundance and their recently highlighted contributions t...

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Detalles Bibliográficos
Autores principales: Wehrspaun, Claudia C., Ponting, Chris P., Marques, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935148/
https://www.ncbi.nlm.nih.gov/pubmed/24616735
http://dx.doi.org/10.3389/fgene.2014.00041