A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma

DNA repair genes that have been inactivated by promoter methylation offer potential therapeutic targets either by targeting the specific repair deficiency, or by synthetic lethal approaches. This study evaluated promoter methylation status for eight selected DNA repair genes (ATM, BRCA1, ERCC1, MGMT...

Descripción completa

Detalles Bibliográficos
Autores principales: Do, Hongdo, Wong, Nicholas C., Murone, Carmel, John, Thomas, Solomon, Benjamin, Mitchell, Paul L., Dobrovic, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935198/
https://www.ncbi.nlm.nih.gov/pubmed/24569633
http://dx.doi.org/10.1038/srep04186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935198/
https://www.ncbi.nlm.nih.gov/pubmed/24569633
http://dx.doi.org/10.1038/srep04186

Ejemplares similares