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A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris

Members of the six-transmembrane segment family of ion channels share a common structural design. However, there are sequence differences between the members that confer distinct biophysical properties on individual channels. Currently, we do not have 3D structures for all members of the family to h...

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Detalles Bibliográficos
Autores principales: Dhillon, Mandeep S., Cockcroft, Christopher J., Munsey, Tim, Smith, Kathrine J., Powell, Andrew J., Carter, Paul, Wrighton, David C., Rong, Hong-lin, Yusaf, Shahnaz P., Sivaprasadarao, Asipu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935203/
https://www.ncbi.nlm.nih.gov/pubmed/24569544
http://dx.doi.org/10.1038/srep04201