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The role of iron in anthracycline cardiotoxicity

The clinical use of the antitumor anthracycline Doxorubicin is limited by the risk of severe cardiotoxicity. The mechanisms underlying anthracycline-dependent cardiotoxicity are multiple and remain uncompletely understood, but many observations indicate that interactions with cellular iron metabolis...

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Detalles Bibliográficos
Autores principales: Gammella, Elena, Maccarinelli, Federica, Buratti, Paolo, Recalcati, Stefania, Cairo, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935484/
https://www.ncbi.nlm.nih.gov/pubmed/24616701
http://dx.doi.org/10.3389/fphar.2014.00025