Dysfunction of outer segment guanylate cyclase caused by retinal disease related mutations

Membrane bound guanylate cyclases are expressed in rod and cone cells of the vertebrate retina and mutations in several domains of rod outer segment guanylate cyclase 1 (ROS-GC1 encoded by the gene GUCY2D) correlate with different forms of retinal degenerations. In the present work we investigated t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zägel, Patrick, Koch, Karl-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935488/
https://www.ncbi.nlm.nih.gov/pubmed/24616660
http://dx.doi.org/10.3389/fnmol.2014.00004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935488/
https://www.ncbi.nlm.nih.gov/pubmed/24616660
http://dx.doi.org/10.3389/fnmol.2014.00004

Ejemplares similares