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mTOR Signal Transduction Pathways Contribute to TN-C FNIII A1 Overexpression by Mechanical Stress in Osteosarcoma Cells

Osteosarcoma is the most common primary malignant bone tumor with a very poor prognosis. Treating osteosarcoma remains a challenge due to its high transitivity. Tenascin-C, with large molecular weight variants including different combinations of its alternative spliced FNIII repeats, is specifically...

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Detalles Bibliográficos
Autores principales: Zheng, Lianhe, Zhang, Dianzhong, Zhang, Yunfei, Wen, Yanhua, Wang, Yucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Society for Molecular and Cellular Biology 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935624/
https://www.ncbi.nlm.nih.gov/pubmed/24598996
http://dx.doi.org/10.14348/molcells.2014.2247