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Chk2 Regulates Cell Cycle Progression during Mouse Oocyte Maturation and Early Embryo Development

As a tumor suppressor homologue during mitosis, Chk2 is involved in replication checkpoints, DNA repair, and cell cycle arrest, although its functions during mouse oocyte meiosis and early embryo development remain uncertain. We investigated the functions of Chk2 during mouse oocyte maturation and e...

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Detalles Bibliográficos
Autores principales: Dai, Xiao-Xin, Duan, Xing, Liu, Hong-Lin, Cui, Xiang-Shun, Kim, Nam-Hyung, Sun, Shao-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Society for Molecular and Cellular Biology 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935625/
https://www.ncbi.nlm.nih.gov/pubmed/24598997
http://dx.doi.org/10.14348/molcells.2014.2259