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ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression

Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine, which is then recognized as guanosine. To study the role of ADAR proteins in RNA editing and gene regulation, we sequenced and compared the DNA and RNA of human B cells. Then, we followed up the findings experimentally with siR...

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Detalles Bibliográficos
Autores principales: Wang, Isabel X., So, Elizabeth, Devlin, James L., Zhao, Yue, Wu, Ming, Cheung, Vivian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935819/
https://www.ncbi.nlm.nih.gov/pubmed/24183664
http://dx.doi.org/10.1016/j.celrep.2013.10.002