Temsirolimus Inhibits Proliferation and Migration in Retinal Pigment Epithelial and Endothelial Cells via mTOR Inhibition and Decreases VEGF and PDGF Expression

Due to their high prevalence, retinal vascular diseases including age related macular degeneration (AMD), retinal vein occlusions (RVO), diabetic retinopathy (DR) and diabetic macular edema have been major therapeutic targets over the last years. The pathogenesis of these diseases is complex and yet...

Descripción completa

Detalles Bibliográficos
Autores principales: Liegl, Raffael, Koenig, Susanna, Siedlecki, Jakob, Haritoglou, Christos, Kampik, Anselm, Kernt, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935828/
https://www.ncbi.nlm.nih.gov/pubmed/24586308
http://dx.doi.org/10.1371/journal.pone.0088203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935828/
https://www.ncbi.nlm.nih.gov/pubmed/24586308
http://dx.doi.org/10.1371/journal.pone.0088203

Ejemplares similares