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Temsirolimus Inhibits Proliferation and Migration in Retinal Pigment Epithelial and Endothelial Cells via mTOR Inhibition and Decreases VEGF and PDGF Expression
Due to their high prevalence, retinal vascular diseases including age related macular degeneration (AMD), retinal vein occlusions (RVO), diabetic retinopathy (DR) and diabetic macular edema have been major therapeutic targets over the last years. The pathogenesis of these diseases is complex and yet...
Autores principales: | Liegl, Raffael, Koenig, Susanna, Siedlecki, Jakob, Haritoglou, Christos, Kampik, Anselm, Kernt, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935828/ https://www.ncbi.nlm.nih.gov/pubmed/24586308 http://dx.doi.org/10.1371/journal.pone.0088203 |
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