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WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern

Members of the WXG100 protein superfamily form homo- or heterodimeric complexes. The most studied proteins among them are the secreted T-cell antigens CFP-10 (10 kDa culture filtrate protein, EsxB) and ESAT-6 (6 kDa early secreted antigen target, EsxA) from Mycobacterium tuberculosis. They are encod...

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Detalles Bibliográficos
Autores principales: Poulsen, Christian, Panjikar, Santosh, Holton, Simon J., Wilmanns, Matthias, Song, Young-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935865/
https://www.ncbi.nlm.nih.gov/pubmed/24586681
http://dx.doi.org/10.1371/journal.pone.0089313